|
Symbol Name ID |
En2
engrailed 2 MGI:95390 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | EEG abnormality |
Abnormal nonverbal communicative behavior |
Delayed speech and language development |
Lack of spontaneous play |
Impaired ability to form peer relationships |
Autism |
Inflexible adherence to routines |
Motor stereotypy |
Restrictive behavior |
Intellectual disability |
Seizure |
| Disease(s) Associated with EN2 | |||||||||||
| autistic disorder |
| Mouse Phenotypes | nervous system phenotype |
abnormal cerebellum development |
abnormal cerebellar foliation |
thin external granule cell layer |
decreased inferior colliculus size |
decreased colliculi size |
abnormal cerebellum morphology |
abnormal cerebellum hemisphere lobule morphology |
abnormal cerebellar granule layer morphology |
abnormal cerebellum vermis lobule morphology |
abnormal cerebellum posterior vermis morphology |
abnormal cerebellum vermis morphology |
small cerebellum |
|
| Availability | Mouse Genotype | |||||||||||||
| En2tm1Alj/En2tm1Alj | ||||||||||||||
| En2tm2Alj/En2tm2Alj | ||||||||||||||
| En2tm3.1Alj/En2tm3.1Alj | * | |||||||||||||
| En2tm3Alj/En2tm3Alj | * | |||||||||||||
| En2tm5.1Alj/En2tm5.1Alj | ||||||||||||||
| En2tm2Alj/En2tm3Alj | * | |||||||||||||
| En2tm5.1Alj/En2tm5.1Alj Gt(ROSA)26Sortm1(cre/ERT2)Alj/Gt(ROSA)26Sor+ (conditional) |
* | |||||||||||||
| En2tm1Alj/En2tm6Alj Gt(ROSA)26Sortm1(cre/ERT2)Alj/Gt(ROSA)26Sor+ (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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